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Introducing cross-Region inference for OpenAI GPT-5.6 models on Amazon Bedrock

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Amazon Bedrock now offers OpenAI GPT-5.6 models (Sol, Terra, and Luna) in more than 25 AWS Regions with cross-Region inference. Learn how US geographic and global inference profiles route requests for higher throughput, how to call the models with the OpenAI and Converse APIs, and how to configure IAM, quotas, and monitoring.

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This post is co-written with Chris Dickens from OpenAI. Amazon Bedrock now offers OpenAI GPT-5.6 models on Amazon Bedrock in more than 25 AWS Regions, with cross-Region inference. Three GPT-5.6 variants support cross-Region inference, Sol, Terra, and Luna, each tuned for a different balance of capability and cost. Cross-Region inference (CRIS) in Amazon Bedrock works through inference profiles, which define a model and the AWS Regions to which Amazon Bedrock can route a request. You call the…

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