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How Benchling secured multi-tenant AI agents with Amazon Bedrock AgentCore

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Learn how Benchling built a defense-in-depth security architecture to run untrusted, AI agent-generated scientific code across thousands of life sciences tenants using Amazon Bedrock AgentCore Code Interpreter in VPC mode, combined with Amazon Route 53 Resolver DNS Firewall and VPC endpoint policies to block data exfiltration, including through DNS.

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When Benchling needed to run AI agent-generated scientific code across thousands of life sciences tenants, their security team found that traditional sandboxing wasn’t enough. Today, this architecture processes more than 600 code execution sessions per day across more than 250 tenants per week with zero security incidents. Standard network controls block HTTP, restrict egress ports, and limit outbound connections. However, DNS resolution is often still permitted, and even when system defaults…

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