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arXiv AI Papers

VIALS: A Benchmark for Visual Interpretation of Artifacts in the Life Sciences

In professional life sciences workflows, scientists routinely interpret visual artifacts (gel blots, microscopy images, plasmid maps, flow cytometry plots, molecular structures, ...) to inform research decisions. We introduce VIALS, a visual question-answering benchmark with 161 such interpretation tasks, spanning the types of artifacts examined throughout experimental workflows in the biotech industry (rather than polished figures from publications and textbooks). While frontier vision-language models can now fluently describe natural images, we find that they are unable to accurately interpret these scientific images, reflecting limitations in domain knowledge and domain-specific visual reasoning capabilities. In contrast, scientists with relevant domain expertise find these visual interpretation tasks straightforward. AI that cannot similarly interpret such images will have limited utility in professional life sciences workflows, where such artifacts are central to how scientists reason, communicate, and make decisions.

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arXiv AI Papers

Re^3Cap: Retrieval-Guided Refinement for Image Captioning Enhancement via Reinforcement Learning

Reinforcement Learning (RL) has demonstrated significant gains in image captioning, yet it is still limited in encouraging Large Vision-Language Models (LVLMs) to explore novel reasoning strategies. This limitation leads to a performance gap between RL and Supervised Fine-Tuning (SFT). In this paper, we argue that multi-modal retrieval can serve as an effective reasoning signal for caption refinement. Based on this insight, we present the Retrieval-Guided Refinement for Image Captioning (Re^3Cap), a retrieval-guided reasoning strategy that enhances image captioning without requiring additional annotations. Instantiated by Caption Refinement Suggester (CRS) and Caption Quality Assessor (CQA), this strategy identifies hallucinations and omissions in image captions, leading to more accurate and detailed descriptions. Extensive experiments demonstrate the superiority of our method in image captioning, even compared with Supervised Fine-Tuning. Especially, Re^3Cap outperforms GRPO with an average improvement of 8.64% in relation reasoning on the COCO-LN500 benchmark.

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arXiv AI Papers

On the Transferability of Agricultural Weed Detection Under Cross-Field Distribution Shift

Accurate agricultural weed detection in real-world field conditions is essential for precision agriculture, enabling targeted intervention and reducing yield loss. Recent work has reported strong detection performance from UAV-based imagery across a range of crops, yet existing approaches evaluate within a single crop and field, leaving practitioners with little evidence that a model trained on one crop will generalize to a new field or crop type. In this work, we characterize where cross-dataset weed-localization performance degrades and which modeling choices recover it, reducing the need to relabel every new deployment field. We introduce a newly collected and annotated UAV image dataset for agricultural weed detection in cotton fields and use it alongside an existing soybean dataset collected under a similar protocol. Using these datasets, we evaluate the performance of several strategies for transferring a detector trained on one crop to another, comparing unsupervised domain adaptive object detection (DAOD) against pretraining on a domain-adjacent source dataset followed by few-shot fine-tuning on the target dataset. Our analysis spans target-domain label budgets from zero to the full target dataset, characterizing the trade-off between adaptation strategy and annotation effort. We find that few-shot fine-tuning with as few as 25 labeled target examples outperforms unsupervised DAOD in our cross-crop comparison, suggesting that source domain selection combined with modest target supervision is more productive than algorithmic sophistication in adaptation.

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arXiv AI Papers

Towards Investigating Residual Hearing Loss: Quantification of Fibrosis in a Novel Cochlear OCT Dataset

Objective: Cochlear implants (CIs) are bionic prostheses that restores hearing via electrical stimulation of the auditory nerve. Hybrid CIs, which use electroacoustic stimulation (EAS), combine residual low-frequency acoustic hearing with CI electrical stimulation. Intracochlear fibrosis, which forms in response to the presence of the implant, may impede residual hearing function and gradually reduce the efficacy of EAS. It is therefore a translational objective to study the formation of cochlear fibrosis in rodents, with the goal of reducing fibrotic burden and improving outcomes for CI patients. Methods: We generate and annotate a novel dataset of optical coherence tomography (OCT) images from chronically implanted guinea pigs as part of an ongoing study focused on implant induced fibrosis. Objectively assessing fibrotic burden in this model, with high resolution and repeatability, presents an obvious use case for computer vision methods. Results: We present the results of several state-of-the-art semantic segmentation models and compare their efficacy for identifying cochlear fibrosis and other relevant annotations, using a new library of manually segmented OCT images. Conclusions: We find that the best performance is achieved by using a modified version of the well-known UNET architecture (which we term 2D-OCT-UNET) that operates on the upscaled OCT input resolution. Significance: For the first time, we have successfully applied computer vision techniques to an OCT dataset of implanted cochleae with fibrosis. Using this deep learning model, the cochlear fibrotic burden calculation can be reliably carried out as we verify in our experimental section. The dataset and the project code are available at: https://github.com/juliadietlmeier/CF-OCT-segmentation

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arXiv AI Papers

An Agentic Approach for Active Data Collection, Travel Behavior Modeling, and Weather-Sensitive Demand Prediction

Travel behavior research increasingly combines digital data collection with predictive modeling, yet these stages are often developed and evaluated separately. This study proposes a three-agent workflow integrating conversational data collection, structured data processing, and behavioral prediction. A chatbot-administered, image-augmented stated-preference survey collected mode choices from student commuters across five predefined weather scenarios, yielding 454 respondent-scenario observations. Weather-related associations were analyzed using a multinomial logit model, while logistic regression and random forest provided machine-learning benchmarks. Nine locally deployed large language models (LLMs), ranging from 2 to 35 billion parameters, were evaluated across four zero-shot prompt-and-context conditions and extended through persona, few-shot, and vision-based configurations. Random forest achieved 69.6% five-class accuracy, while the best text-only zero-shot LLM reached 69.9% without task-specific fitting. Habitual travel information produced the most consistent gains, Expert framing generally outperformed Role-Play, and persona information was most useful when habitual travel information was unavailable. Few-shot prompting improved prediction for several models, with gains stabilizing after a small number of examples. Using the same weather images shown to respondents, the best vision-based configuration reached 71.5% five-class accuracy, indicating that visual context may provide additional predictive information for selected models. Overall, the study shows how conversational surveys, structured data processing, conventional behavioral modeling, machine learning, and multimodal LLM prediction can be coordinated within an auditable multi-agent workflow.

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arXiv AI Papers

Prompt-Conditioned Channel Attention for Hierarchical Feature Modulation toward Anatomy-Agnostic Segmentation

Anatomically plausible segmentation remains challenging because of low contrast, ambiguous boundaries, and modality-specific artifacts. Interactive segmentation has emerged as a promising strategy to guide feature extraction and improve localization, particularly in structurally ambiguous regions. However, existing methods integrate prompts through late-stage fusion and lack explicit mechanisms for prompt-driven channel-wise modulation across hierarchical feature representations, limiting their ability to capture deeper contextual and modality-specific variations. To address these limitations, we introduce Prompt-Conditioned Channel Attention (PCCA), a novel modulation mechanism that enables deep, hierarchical integration of semantic prompts within encoder-decoder networks. PCCA extracts compact channel descriptors via pooling, projects them into a shared space, and fuses them through a gated excitation mechanism to compute prompt-aware channel attention weights. These weights adaptively recalibrate feature responses across multiple network stages, enabling prompt-conditioned, semantically enriched hierarchical representations. Building on this, we propose PROMISE-Net, instantiated in two network variants: a convolutional model (PROMISE-CNN) and a transformer-based model (PROMISE-Txformer). Across the ISIC-Lesion, Kvasir-Polyp, CAMUS-Cardiac, and Kvasir-Instrument benchmarks, integrating PCCA into PROMISE-CNN yielded relative IoU gains of 10.4%, 8.7%, 0.8%, and 3.4%, respectively, over the baseline U-Net, while PROMISE-Txformer achieved corresponding gains of 7.6%, 23.0%, 2.1%, and 1.1%, respectively, over the baseline UNETR. These results show consistent improvements across architectures, imaging modalities, and anatomical targets, establishing PCCA and PROMISE-Net as a scalable, generalizable framework for prompt-aware hierarchical feature modulation in medical image segmentation.

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arXiv AI Papers

DARS: Dual-Level Credit Assignment RL with Structured Reasoning for Instruction-Based Image Editing

Instruction-based image editing uses a planner-renderer pipeline: a vision-language model (VLM) first converts the instruction into an edit plan, and a diffusion model then executes that plan. Training such systems with only final-image rewards is inefficient because a poor edit does not reveal whether additional optimization should place more emphasis on the planner or the renderer, and even planner-dominant cases remain difficult to localize within a free-form reasoning trace. We present DARS, a reinforcement learning framework for dual-level credit assignment in this two-stage setting. Across modules, multi-plan multi-render rollouts estimate between-plan and within-plan reward variability for soft module routing, while rollout mean rewards provide hardness estimates for an adaptive curriculum. Within the planner, a four-field structured reasoning output enables a prefix-gated reward and token-level advantage reweighting, turning outcome-level feedback into localized supervision. Experiments on five benchmarks show that DARS outperforms a Joint~RL baseline with the same backbone, data, reward model, and rollout budget, with the largest gains on reasoning-intensive edits.

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arXiv AI Papers

Discrete Diffusion Inference-Time Control with Nested Sequential Monte Carlo

We study inference-time control for text generation in discrete diffusion language models, where the goal is to steer sampling toward sequence-level rewards without retraining. Prior work in this domain has focused on particle-based methods such as best-of-n sampling and bootstrap sequential Monte Carlo, which may suffer from overoptimism and weight degeneracy, respectively. We address these limitations using nested sequential Monte Carlo methods. We formulate nested SMC (NSMC) and fully-adapted nested SMC (FA-NSMC) for Feynman--Kac steering, identifying and correcting errors in prior formulations that lead to biased final estimates. We evaluate these methods on toxicity and fluency steering tasks, showing that NSMC and FA-NSMC consistently outperform best-of-n and bootstrap SMC.

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arXiv AI Papers

SAE-Xplainers: Rule-Based Feature Interpretation for Extreme Earth Events

The emergence of large-scale Weather and Climate (W&C) datasets offers new opportunities for modeling extreme Earth events (ExEE) and their impacts using deep learning. However, their adoption in operational settings remains limited by the lack of models' interpretability. While for conventional text and image modalities, tools such as Sparse Autoencoders (SAEs) have proven effective for extracting human-understandable concepts, their use for the analysis of ExEE remains challenging due to the nature of W&C data. To address this, we introduce (i) a geographic location-based modulation of the inputs of SAE to capture the local semantic meaning of environmental patterns, and (ii) an ensemble of rule-based SAE-Xplainers to interpret the resulting high-dimensional features derived from complex, multi-modal environmental predictors. We evaluate our method on three ExEE types: the prediction of fires, and the detection of tropical cyclones and atmospheric rivers. We show that SAE input modulation improves both reconstruction performance and feature utilization, and that our SAE-Xplainers enable faithful interpretation of complex climatic patterns by unfolding them into human-understandable rules that are consistent with the scientific literature, while also supporting the identification of feature absorption.

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