The ever-expanding volume of the chemical literature offers unprecedented opportunities to generate novel and impactful hypotheses. However, the bottleneck lies in efficiently navigating this vast knowledge base to formulate high-quality, experimentally meaningful insights. While Large Language Models (LLMs) show promise for this task, existing methods often rely on static inspiration corpora, predefined heuristics, or laborious human-in-the-loop pipelines and decision-support frameworks that limit scalability and novelty. In this work, we propose an automated approach, a Memory-augmented, Adaptive, Incremental, and Literature-grounded (MAIL) framework for hypothesis generation in chemistry. Our MAIL method formulates hypothesis generation as a temporally grounded, memory-driven reasoning process, where hypotheses emerge from an evolving conceptual path that continuously accumulates and reinterprets prior knowledge. We evaluated the MAIL framework on a public TOMATO-Chem dataset and a newly curated and disseminated high-novelty nature/science challenge (HN-NS) dataset. Across both datasets, MAIL generates structurally coherent and mechanistically plausible hypotheses, achieves the highest MIOS and MPOS by more effectively recovering the central ideas and methodological elements of the historical target hypotheses, and obtains the highest overall expert-evaluation scores for scientific quality. These results demonstrate the potential of LLMs to autonomously explore chemical domains and generate hypotheses that are both innovative and chemically plausible.
Multimodal large language models (MLLMs) can memorize identity-specific facts about people in their fine-tuning data, creating privacy risks when a person requests deletion. Existing MLLM unlearning methods often assume access to retain images or ground-truth answers during deletion, which is unrealistic in many practical scenarios. We study identity unlearning when retain images are unavailable at deletion time. Our analysis shows that identity and visual-perception questions occupy distinct regions in fine-tuned hidden states and are organized differently: identity questions cluster by person, whereas perception questions cluster by question type. This suggests that identity knowledge can be suppressed without erasing general visual perception. Building on this observation, we propose AIM, a two-stage method that anchors an identity-forgetting target with a universal visual prompt and then matches the vision encoder to that target under a Fisher-based constraint. Extensive experiments show that AIM achieves competitive identity forgetting while preserving non-deleted identities, prior knowledge, and visual perception on the same images.
Assine o Pro, sem anúncios
Faça upgrade para uma leitura sem interrupções e acesso prioritário a novas fontes.
We study the scaling behavior of learning rate and batch size in pretraining dense large language models on English-prevalent corpora. Beyond scaling jointly optimal learning rates and batch sizes, we investigate their marginal evolution with model capacity and data scale and develop a model that captures these relationships. As we employ a Warmup-Stable-Decay learning rate schedule, we further investigate the gains from learning rate annealing over a broad range of hyperparameters settings, models and data budgets, and whether the optimal learning rate and batch size transfer between the stable and decay phases. Finally, we characterize the dependence of loss on model capacity and dataset size, evaluating recently proposed scaling forms that explicitly model their interaction. We find these approaches particularly effective at capturing both undertraining and overtraining regimes across our experiments. This study establishes a first baseline and scaling procedure for the development of future OpenEuroLLM models. We open-source the complete collection of pretraining runs used in this study.
On-policy self-distillation (OPSD) improves reasoning by training a problem-only student on its own rollouts using dense token-level supervision from a privileged teacher that also sees a reference solution. However, standard OPSD treats the teacher distribution as a fixed target along the student's rollout and updates only the student %, although -- even though privileged conditioning does not guarantee that the teacher always provides the most appropriate target for problem-only reasoning. This one-way supervision can therefore misdirect the student when the teacher distribution is misaligned with valid student reasoning. We therefore introduce Verifier-Informed Student-to-Teacher Adaptation (VISTA), which preserves the standard OPSD student update while using outcome-verified rollouts to adapt the teacher toward the student distribution. Within each verified rollout, VISTA further restricts this adaptation to the top-k positions with the largest teacher--student KL divergence. Notably, VISTA reuses the rollout and loss function from standard OPSD, introducing no additional sampling or separate reward objective. Across AIME24, AIME25, and HMMT25 with Qwen3 models at 1.7B, 4B, and 8B, VISTA achieves the highest Avg@12 at every scale, improving over OPSD by 0.6, 0.7, and 2.1 points, respectively. These results demonstrate the value of student supervision from outcome-verified rollouts and highlight student-to-teacher adaptation as a promising direction for OPSD.
Industrial panel operation is knowledge-intensive and safety-critical. Beyond control recognition and action generation, execution must satisfy constraints in operation manuals and safety regulations. While foundation-model-based planners show strong semantic capability, they typically lack computable, localizable, and reproducible mechanisms for violation detection and repair. To address this, we propose PanelShield, a verifiable closed-loop safety planning framework for manual-guided industrial panel operation. The framework generates parameterized action primitive sequences from task-relevant manual evidence and applies dual formal verification with LTL and a Safety FSM to enforce cross-step temporal correctness and local transition legality. When violations occur, it outputs a structured counterexample with the earliest violating step and cause, enabling targeted repair and re-verification. We build a multi-level long-horizon planning benchmark covering three representative industrial device panels, and evaluate the framework in simulation and real-world robotic experiments. Results show that PanelShield improves complex safety-constrained task performance over foundation-model-only planning baselines while reducing the violation rate to 2.7%, with 4.1 s total latency. Real-world experiments demonstrate end-toend feasibility. Overall, PanelShield offers a verifiable approach to robotic panel operation that balances flexibility, safety, and auditability.
A federal judge ruled the Trump administration illegally labeled Anthropic a supply chain risk, handing the AI company a victory as its second Pentagon lawsuit…
Sandhya Devanathan will oversee some OpenAI operations across Southeast Asia and Australia in her new role.