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1836documentos

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arXiv AI Papers

Medical Image Segmentation: Foundation Model Adaptation versus Task-Specific Training

Foundation models pretrained on large natural-image collections are increasingly adapted for medical image segmentation, in the expectation that they will replace models trained for each task. Most comparisons, however, use data from the training distribution and a single task-specific baseline whose configuration is rarely justified, and therefore provide limited evidence of performance at new clinical sites. It also remains unclear how much of a foundation model must be adapted, and what determines this. We adapted a foundation model, DINOv2, with strategies ranging from tuning only its bias terms to full fine-tuning, and compared it with U-Nets and ResU-Nets trained from scratch. Experiments covered colonoscopy, breast ultrasound and dermoscopy, with testing on held-out data from the training source and on independent datasets from other institutions. The adapted foundation model generalised better on every external dataset. Within the training distribution, the task-specific models remained competitive when training data were abundant, and delineated boundaries more precisely, while the foundation model more often missed small lesions. Only a small fraction of the foundation model required adaptation, and the capacity needed was determined by the imaging domain rather than by the adaptation method. A widely used polyp test set was also found to duplicate images from another benchmark. Foundation-model adaptation is therefore warranted where models must work across sites, with capacity selected on the target domain.

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arXiv AI Papers

Toward Foundation Detection Models via Example-Based Grounding in EM-DETR

DeepLearning (DL)-based Computer-Aided Diagnostic (CAD) systems have shown great promise in supporting clinicians, but their performance heavily depends on the availability of large, well-annotated datasets. In medical lesion detection, the scarcity of comprehensive, stan dardized annotations and the heterogeneity of existing datasets limit the development of robust foundation models. In this work, we introduce a novel approach to building a multi-domain foundation model for le sion detection by integrating diverse medical image datasets annotated for both anatomical structures and abnormalities. We first propose a student-teacher training strategy to effectively combine datasets with heterogeneous label spaces, mitigating catastrophic forgetting, and im proving feature learning. In addition, building on our previously pro posed example-based EM-DETR framework, we adapt it to jointly learn from multiple domain-specific datasets, enabling fine-grained, example driven detection across modalities. Our model achieves state-of-the-art (SOTA) results, with image-level AUC scores exceeding previous SOTA by 1% point on four key findings in CXRs. We achieve a leading mAP50 in CXRs and mammography, surpassing EM-DETR trained on a single dataset by 2-3% points. This approach paves the way for scalable foundation models in medical imaging that leverage heterogeneous data while maintaining robust and generalizable performance.

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arXiv AI Papers

When Does the Real Wiring Win? Testing connectome structure-function claims against unmeasured physiology

Connectome-constrained models are often used to argue that a measured wiring diagram outperforms shuffled or rewired wiring, and hence that structure shapes function. Such comparisons can confound wiring with how the models are tuned: a connectome fixes who connects to whom, not the excitability, gains or plasticity rates the model also needs, and modellers often tune these until the real-wiring model works. We separate three estimands: physiology tuned on the real wiring and transferred to nulls (P1), each wiring tuned on its own (P2), and P2 restricted to physiology consistent with independent data (P3). The biases involved are known in machine learning (under-tuned baselines, inherited weights, winner's curse); we measure what they do to biological conclusions, using synthetic ground truth, placebo nulls and three Drosophila circuit models. Some claims survive every protocol we test: segregated reward and punishment dopamine improves learning, and head-direction topography is required for a persistent bump. Others do not. In the mushroom body, the real Kenyon-cell output wiring beats a cross-subtype identity shuffle by 0.09 under P1 and P2 but loses to it by 0.09 under P3 (95% CIs exclude zero; held-out runs confirm). The verdict is set by the share of alpha'beta' cells among active Kenyon cells, which P1 selects low; at the share implied by imaging (about 44%) the real-wiring model fails to learn, exposing a model inadequacy rather than a deficit of the fly's wiring. In flyvis, P1 penalises a mirrored connectome, which has a constructed solution within 0.07 (median) of the real error, more than a spatially shuffled one in 50 of 50 members; the ranking survives ten-fold longer retraining but depends on the checkpoint at fifty-fold. A credible structural claim needs matched optimisation, data-constrained physiology and a model that still works there.

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arXiv AI Papers

C^2-Routing: Complementary Cropping and Compression for Efficient Vision-Language Inference

Visual Question Answering (VQA) imposes substantial computational overhead on vision-language models (VLMs), motivating model-agnostic input reduction methods that can be readily applied across diverse VLMs, including in black-box settings. Simply enforcing a visual-token cap reduces computation, but it can discard information needed to answer the question. A single reduction strategy also struggles to accommodate different scenarios. Our key observation is that cropping and compression are complementary: cropping highlights small targets and local details, whereas whole-image compression better preserves context for large targets or distributed evidence. Based on this observation, we propose C^2-Routing, which adaptively selects cropping or compression according to the input image and question. Since both strategies may still discard key information, we further design a safety gate that uses the predicted joint correctness distribution under original and reduced inputs to guide fallback and protect accuracy. To accommodate consumer GPU resource constraints, all training and evaluation experiments run on RTX 3090 GPUs. To measure gains beyond token capping, we use full-image baselines with the same cap of 1,024 visual tokens. We conduct extensive evaluation on three VLMs and 18 datasets spanning local details, global scenes, scene text, and documents. With the visual budget already capped, C^2-Routing further reduces end-to-end FLOPs by 36.53% and visual tokens by 42.36% on average, with a mean relative task-score decrease of only 0.77%.

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arXiv AI Papers

Bayesian inverse problems and epidemic-threshold uncertainty for a heterogeneous SIS reaction-diffusion model

We study Bayesian inference of persistence from early observations of a heterogeneous susceptible--infected--susceptible (SIS) reaction--diffusion model with standard incidence. We show that the leading prevalence dynamics depend on the unknown coefficients only through the difference between the transmission and recovery rates and the infected diffusivity. The same pair determines the principal eigenvalue whose sign governs persistence, so early prevalence can inform the threshold even when the individual rates remain uncertain. We prove global weak well-posedness and quantitative parameter stability for the SIS system and use the resulting observation-map estimates to establish Bayesian well-posedness. For an initial infection of size , we derive a uniform second-order expansion that describes how the separate rates enter prevalence. Incidence depends explicitly on transmission at leading order. When the noise standard deviation is proportional to , we prove O() convergence in Hellinger distance of the nonlinear posteriors to their low-prevalence limits for both prevalence alone and joint prevalence and incidence data. We bound the principal eigenvalue using the growth rate of the infected L^2 norm between two times. This rate gives a lower bound for the full nonlinear system, and the upper bound separates spatial transients from nonlinear saturation. Uniform spectral estimates and bounds on infection size and measurement error give sufficient conditions for persistence and extinction. We also bound the error in posterior persistence probabilities under forward and eigenvalue approximation, accounting for posterior mass near the threshold. Numerical examples illustrate threshold inference and the predicted (O()) convergence of the nonlinear posteriors to their low-prevalence limits in Hellinger distance.

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arXiv AI Papers

UGG: Unified Generative Geometry Model

Understanding 4D scenes is a core challenge in visual intelligence, requiring models to jointly capture scene geometry, appearance, and dynamics from partial observations. However, existing approaches are subdivided into feedforward models for direct geometric prediction, and generative models for visual synthesis. We introduce UGG, a unified framework for 4D scene understanding that jointly models RGB video and geometric representations such as depth and camera pose. By assigning different noise levels across modalities and time, UGG formulates visual generation and geometric prediction as conditional completion within a single generative model. This flexible formulation enables the model to learn from diverse, heterogeneous datasets with different subsets of geometric and visual annotations. Furthermore, our generative formulation enables inference-time search over multiple plausible scene hypotheses, using geometric evidence extracted from observed RGB frames to improve geometric prediction without ground truth geometry. We demonstrate UGG's effectiveness over non-unified baselines across camera-controlled video generation, depth estimation, and camera pose prediction, including in challenging sparse observation settings. Code and visualizations are available at https://ugg-model.github.io/

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arXiv AI Papers

Causal Concept Explanations for Deep Neural Models

Concept-based explanations in neural models are important for the development, certification, and adoption of autonomous systems. Yet, interpretability remains correlational. Without methods to guide and quantify causal relationships between explanations, a concept explanation can be provided without being necessary or sufficient for the observed output thereby appearing correct while misleading. We introduce Causal Concept Wrapper Network (CCW-Net), the first use of interventional mediation analysis from fields such as economics, medicine, and epidemiology as a training objective to align causal effects of concept-based explanations with a model's output. We further apply mediation analysis as an evaluation tool to quantify, per concept label combination, how much of any model's output is causally attributable to each concept explanation. As a training objective, CCW-Net shapes a model's concept representations such that they are both necessary and sufficient for the outputs they are credited with and independent of other concepts' contributions. Counterfactual concept representations anchor a set of causal alignment criteria: necessity, sufficiency, and independence. Necessity drives irrelevant concept effects toward zero, sufficiency ensures relevant concept representations fully reconstruct a model's output, and independence enforces the total effect decomposes linearly across concepts. We evaluate CCW-Net across aircraft control, driving, and image classification. CCW-Net provides a step toward concept-based explanations that are not merely interpretable, but quantifiably causal, supporting safer evaluation, certification, and deployment of transparent and trustworthy neural models.

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arXiv AI Papers

Blurring the Block Boundaries: Overlapping Block Denoising for Efficient Diffusion Language Models

Diffusion Language Models (DLMs) have emerged as effective alternatives to autoregressive models for latency-critical tasks, enabling faster token generation. Recent advances employ block diffusion with self-editing capabilities, where each block refines tokens iteratively before advancing to the next one. Yet each block is only as fast as its slowest token, and the next block cannot start before it. We suggest Blurring the Block Boundaries (B3), a novel method with which two blocks are refined in parallel within a shared forward pass. B3 calibrates itself on the fly, opening the next block only once the model is ready to start generating it. It is a training-free and hyperparameter-free acceleration method which seamlessly integrates within any self-editing block diffusion model. Evaluated on state-of-the-art DLMs across 10 diverse datasets spanning varied tasks and difficulty levels, B3 results in on par generation quality and 11.5-14.5% speedup compared to the base model, pushing the Pareto frontier for latency-quality trade-offs in DLM inference.

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arXiv AI Papers

An Energy-Based Perspective on Machine Learning

Energy-based models (EBMs) define a distribution through a scalar energy, p_θ(x)(-E_θ(x)), and are usually presented as one model family among many. This tutorial has a broader goal: beyond introducing EBMs, it uses them as a single lens that connects the different aspects of machine learning. Any EBM is specified by three choices, the energy, which determines what the model represents; the inference procedure, which samples from or optimizes the energy; and the learning method, which fits the energy to data. We first develop these components, including sampling, variational inference, and learning by maximum likelihood, noise contrastive estimation, pseudolikelihood, score matching, and adversarial training, and show that the learning methods share one contrastive structure. We then show that discriminative models, generative models such as GANs, normalizing flows, diffusion and autoregressive models, representation learning methods such as contrastive learning, word2vec, BERT, denoising auto-encoders, and diffusion representations, reinforcement learning with EBM policies and world models, inverse reinforcement learning, and planning, as well as inference-time computation with verifiers, are all EBMs that differ in these three choices, mostly in how they handle the partition function and sampling. This view explains existing methods, organizes them into a common framework, and suggests new algorithms by replacing one component while keeping the others, with composition of energies as a principled way to combine learned models at inference time.

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arXiv AI Papers

Cognitive Mapping of Learning by Thinking Mechanisms in Large Language Models

Large language models (LLMs) increasingly exhibit capabilities that resemble human Learning by Thinking (LbT), the acquisition of new insight through internal processes such as explanation and reasoning, without new external input. A systematic account of the cognitive mechanisms behind these capabilities, and of their limits, remains underdeveloped. This paper proposes a Cognitive LbT Framework that maps four mechanisms (Reflective Reasoning, Synthetic Memory Formation, Internal Simulation, and Conceptual Self-Organization) onto computational processes in LLMs. Drawing on representative methods, including chain-of-thought prompting, self-consistency, self-reflection, Tree-of-Thoughts search, Self-Instruct, and self-taught reasoning, the analysis argues that selected methods can functionally approximate aspects of these mechanisms and can improve performance on some tasks without additional labeled examples, although this does not always constitute durable learning in model parameters. For example, Self-Instruct generated approximately 52,000 instructions from 175 seed tasks and reported a 33% absolute improvement on Super-NaturalInstructions (Y. Wang et al., 2023). The same mechanisms also produce characteristic failures, including hallucination diffusion, model collapse, concept drift, and high computational cost. These failures are not isolated technical defects but follow from four structural asymmetries between LLMs and human cognition: the identity of generator and monitor, closed learning loops without external grounding, symbolic rather than sensorimotor simulation, and the cost of inference-time computation. The framework yields testable propositions about when LbT in LLMs should succeed or fail and offers a structured basis for designing more reliable autonomous learning systems.

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arXiv AI Papers

Forward-Value Discretization: Faster Stochastic Diffusion Sampling Without High-Order Approximation

Stochastic diffusion samplers often require substantially more neural function evaluations (NFEs) than deterministic samplers to achieve comparable sample quality. Although higher-order discretization accelerates deterministic sampling, its benefits for stochastic sampling remains unclear. We establish matching upper and worst-case lower bounds showing that stochastic samplers with higher-order approximations remain first-order convergent, even with exact score functions. Thus, increasing the approximation order does not generally improve the convergence order. Motivated by this limitation, we introduce forward-value discretization, a training-free framework that evaluates the data/noise prediction model at a lookahead estimate constructed from previous predictions. For deterministic sampling, the resulting Forward DPMSolver (F-DPMSolver), improves sample quality at low NFE budgets through its DDIM-based variant, despite remaining first-order convergent. For stochastic sampling, we develop Forward DDPM (F-DDPM), which evaluates the model at a cleaner lookahead point adjusted for subsequent noise injection. This estimate reuses both the previous model prediction and the previously injected noise. Both variants admit first-order convergence guarantees with one model evaluation per iteration. Across CIFAR-10, ImageNet, FFHQ, and LSUN, F-DDPM consistently achieves lower FID than the evaluated stochastic baselines at matched NFE budgets. With 1.5 times as many NFEs as deterministic baselines, it achieves competitive sample quality, narrowing the practical efficiency gap between stochastic and deterministic sampling. Code is available at https://github.com/Na-Li66/F-DDPM.

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arXiv AI Papers

Where Do Vision-Language Models Get Left and Right? Position-Code Counterfactuals in Qwen2.5-VL, Qwen3-VL and InternVL3

A vision-language model may take left-right direction from the orientation of image content within patches, its vision transformer's (ViT) position code, or token positions and order in its language model (LLM). Ablations show the ViT code is necessary; we test sufficiency by mirroring only a position code. In Qwen2.5-VL-7B, Qwen3-VL-4B and InternVL3-2B, mirroring ViT width positions reproduces the flipped-image answer on 84.3-93.2% of CV-Bench left-right questions (Qwen2.5-VL-3B: 87.5%, partly a left fallback). With two options, this also counts disruption; a half-grid shift flips most answers too. With the ViT code intact, LLM-side id and token-order mirrors change few left-right answers in all three series (a weak id test in Qwen2.5-VL). In Qwen2.5-VL-7B the effect sits in the global-attention ViT blocks, mostly the last. On What'sUp, flipping content and token order, not the position code, keeps more on/under than left-right answers at the flipped-image answer. Post hoc analyses qualify these results. On CV-Bench items with located objects, random permutations flip 18.9-31.0 points more answers when reversing the objects' order than when keeping it. On What'sUp, in Qwen2.5-VL and Qwen3-VL, the share of the left-right changes made by random permutations that land on the mirror relation is mostly below chance. Counted as returns to the original answer, the What'sUp contrast of support with left-right relations is clear only in InternVL3-2B. Most remaining errors give the same relation whichever object is asked about, suggesting that repair may target relation binding, object localization or use of the reference object.

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