unsloth/Qwen-Image-2.1-GGUF
New text-to-image model. Tags: gguf, quantized, unsloth, qwen, image-generation, text-to-image, en, zh
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Imagen y video
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AI-Driven Neural Surrogates for In Silico Design of Cognitive-Affective Neuromodulation Targets
In neuropsychiatry, the primary goal is often not only to decode brain activity but to change it, for example to lessen a negative affective bias or an overly salient memory. Motivated by control theory, we develop an AI-driven neural-surrogate framework that proposes candidate representational changes and tests their predicted perceptual effects from snapshots of stimulus-evoked fMRI activity, without physical stimulation. The framework combines fMRI decoding, deep generative modeling, and constrained latent-space steering. Valence and memorability are used only as worked examples. Using more than 36,000 image-fMRI observations from four deeply sampled Natural Scenes Dataset participants, subject-specific models recovered coarse generative structure from visually responsive cortex (two-way identification, 0.79-0.88; chance, 0.5). Graded perturbations were reconstructed as images and evaluated with automated scorers and human ratings from 7,200 trials by 18 participants. In the primary VDVAE model, valence shifted from -0.61 to +1.03 SD and memorability from -1.34 to +1.45 SD; a later Versatile Diffusion refinement reduced or altered these effects. Across five perturbation levels, human valence ratings moved in the predicted direction under the linear time-correction model (mean slope, 0.038 SD per unit of alpha; 95 percent CI, 0.003-0.074; positive in 16 of 18 participants). Perceived memorability did not change reliably. Baseline agreement with the automated assessor was suggestive for valence (r = 0.30) and weak for memorability (r = 0.10). Extreme perturbations drifted from the original stimulus, so intended change must be weighed against loss of fidelity. These findings provide a falsifiable upstream method for designing and behaviorally testing candidate representational targets for future neuromodulation in psychiatry, while marking the limits of the present static approximation.
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FFM-CP: Cross-Backbone Fusion of Vision-Language Foundation Models for Few-Shot Computational Pathology
Pathology vision-language foundation models vary in performance across diseases and tasks, with no single model consistently performing best. The high cost of expert pathology annotation can also limit the labeled data available for task-specific adaptation. Combining complementary pretrained representations is a potential approach to these limitations, yet learning an effective fusion from few labeled examples remains challenging. We introduce Few-shot Fusion Foundation Models of Computational Pathology (FFM-CP), which is a framework that combines multiple pathology vision-language models in the few-shot learning setting. The framework first aligns heterogeneous representations using a closed-form Orthogonal Procrustes transformation estimated from corresponding support images. This alignment preserves within-model feature geometry without training an additional alignment network. Within the aligned space, a unified graph enables information exchange across backbones by jointly refining support-image features and visual and textual class prototypes. These refined representations support complementary text-prototype and case-retrieval branches that capture semantic class knowledge and within-class visual variation, respectively. Each branch learns to combine predictions from all ordered backbone pairs, allowing queries encoded by one model to draw on evidence represented by another. We evaluate three backbone combinations on six histopathology datasets at 4, 8, and 16 shots per class. FFM-CP achieves higher mean macro-F1 than the strongest individually adapted member of each fused set in 50 of 54 comparisons. These findings suggest that combining complementary pretrained representations can improve histopathological classification when annotations are limited.
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OpenAI nabs key Patreon execs ahead of upcoming announcement
OpenAI has hired three former Patreon execs to anchor its product strategy for creators. After starting the creator subscription platform 13 years ago, co-founder and…
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Private Decentralized Optimization with Noise Reduction and Bias Correction
Private decentralized learning is affected by sampling noise, privacy noise, and decentralized bias under heterogeneous data. We propose Private Recursive Decentralized Optimization (PRDO). PRDO uses recursive estimation with same-batch gradient differences to reduce estimation errors caused by sampling and privacy noise, while its Exact Diffusion component corrects decentralized bias arising from data heterogeneity. Our analysis establishes a nonconvex convergence bound without assuming uniformly bounded data heterogeneity across nodes. It further gives a sufficient condition under which recursive gradient differences yield strictly lower query sensitivity than private Exact Diffusion, together with an example that rigorously satisfies this condition. Experiments show improved accuracy over the evaluated baselines.
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InternW0: A Foundational Physical World Model for Efficient Real-World Interactions
Physical intelligence requires more than predicting how the world may evolve: predictions must remain actionable as the world continues to change. We introduce InternW0, the first instantiation of the InternW physical world model series from Shanghai AI Laboratory, built around omnimodal interfaces, asynchronous multi-frequency processing, and local physical modeling under partial observations and external influences. InternW0 jointly learns future visual dynamics and continuous robot control through an asymmetric video--action architecture with flow matching. A high-capacity video expert provides longer-horizon predictive context, while a lightweight action expert operates at a faster timescale. Instead of regenerating the future for every action update, InternW0 reuses layerwise K/V and adapts it to newly observed states through observation-conditioned context routing. Domain-specific interfaces and soft prompts support heterogeneous embodiments, while contact-aware post-training incorporates force and tactile signals for contact-rich manipulation. We train InternW0 on approximately 7,200 hours of heterogeneous robot and egocentric data, including EgoLab, a 275-hour real-laboratory egocentric dataset. Evaluation spans simulation benchmarks and real-world scientific tasks, including a 15-stage metal--organic framework synthesis workflow and 5-stage contact- and force-aware dexterous manipulation for general-purpose quantitative pipetting. These results advance scalable, asynchronous, and science-native physical world models for universal and efficient real-world interactions.
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Pheno-GS: Phenoscape-scale Geodesic Sinkhorn
High-throughput single-cell data is now collected across large patient cohorts. Understanding patient-level heterogeneity from cellular-level data motivates phenoscaping: embedding each single-cell distribution as a "datapoint," with distances given by optimal transport (OT). Computing geometry-aware OT at this scale, between all pairs of patient datasets, remains an open challenge, since existing methods either rely on Euclidean ground metrics that distort manifold structure or fail under sparse, unevenly sampled, or large-scale data. We present Pheno-GS (Phenoscape-scale Geodesic Sinkhorn), which computes accurate, scalable geodesic transport distances under noisy, unbalanced, large-scale settings via three components: (1) graph connectivity regularization for well-defined geodesics on sparse/disconnected manifolds; (2) an unbalanced OT formulation via KL marginal penalties; and (3) a batched matrix algorithm computing all pairwise distances in one heat diffusion (over 200 faster than Geodesic Sinkhorn for 500 distributions). We validate Pheno-GS on synthetic benchmarks and a CyTOF perturbation dataset.
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SHRAV: State-Hypothesis-Reason-Action-Verify Framework for Physical Modeling and Inverse Design
Physical modeling and inverse design require computation that can continue from reusable state. We introduce SHRAV, an architecture-independent computational framework organized around State, Hypothesis, Reason, Action, and Verify. Its central mechanism is a state-continuation core with declared reuse boundaries and explicit roles for learned evolution and numerical quantities. Forward configurations evolve predictive state and read out physical responses; inverse-design configurations additionally generate target-directed modifications and consume evaluator feedback. Electromagnetic world-model studies are mapped to forward configurations, with selected readout and reuse diagnostics reported here. Computational lithography demonstrates an inverse-design configuration: four fixed-weight design updates improve thresholded aerial-image intersection-over-union from 0.5313 to 0.8153 under independent scalar-pupil replay, with maximum absolute prediction-replay difference approximately 0.000824 between predictor estimates and independent replay.
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InGuard: Towards Generalized Inner Guardrail for Safe Text-to-Image Generation
Modern text-to-image (T2I) models generate high-quality images from arbitrary user prompts, yet they can just as easily produce not-safe-for-work (NSFW) content. Conventional outer guardrails consist of two components: a prompt classifier that checks for risk before generation, and a post-hoc image classifier that checks the fully generated image. In this design, both classifiers operate outside the generation pipeline and do not use the model's own representations. This separation can limit prompt-screening accuracy, while the image-side check runs only after the full generation cost has been spent. Moreover, a flagged prompt can only be rejected, even when it could be adjusted to produce a safe image. In this work, we propose the Inner Guardrail (InGuard), a safety framework that works inside the pipeline on the model's own representations, leaving base-model parameters untouched. First, a risk classifier grades each prompt as unsafe, risky, or benign based on the text encoder's embeddings, with no external language model. Second, SAGE (Soft-gated Asymmetric Guardrail for Embeddings) modifies the embeddings of risky prompts, aiming to return a safe image instead of a refusal. Third, a latent detector checks the one-step clean latent estimate midway through denoising, reaching nearly image-level performance and halting generation when risk is detected. We also construct the RevGen Safety Benchmark to evaluate T2I safety under realistic conditions: 10,000 prompts built through real-image reverse generation, with a rewriting step that supplies controlled intellectual-property (IP) characters, covering graded porn/gore risks, categorical IP risks, and benign negatives. Across five open-weight T2I models, InGuard reaches 97.9-98.8% safety rate, matching or exceeding the outer guardrail, with 57.5-73.5% less benign disturbance, ~3.7x fewer parameters, and 50-55.6% of denoising steps skipped.
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inclusionAI/Ming-Image-0.1-Design
New text-to-image model. Tags: diffusers, text-to-image, image-generation, graphic-design, text-rendering, rgba, license:mit
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At AI Day Singapore, NVIDIA and Partners Showcase AI Advancements Across Southeast Asia
NVIDIA AI Day Singapore, which takes place Sept. 22-23 at the Raffles City Convention Centre, is offering attendees opportunities to explore the hands-on training, expert-led sessions and advanced tools to accelerate their work in AI and high-performance computing. At the event, NVIDIA and its partners are showcasing breakthrough AI advancements across the Southeast Asia region […]
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Flash-dLLM: IO-Aware KV Caching and Parallel Decoding for Fast, Memory-Efficient Diffusion LLMs
Diffusion Large Language Models (dLLMs) have recently emerged as a promising alternative to autoregressive LLMs by enabling non-autoregressive text generation. However, their practical deployment remains limited by inefficient inference, largely due to the absence of effective Key-Value (KV) caching and scalable parallel decoding mechanisms. Existing acceleration methods typically study KV caching and parallel decoding in isolation, overlooking the I/O bottlenecks that arise when cache reuse and parallel token verification are jointly applied. In this work, we introduce Flash-dLLM, a training-free inference acceleration framework for fast and memory-efficient dLLMs. Flash-dLLM first identifies GPU memory I/O as a dominant bottleneck in KV-cache-enabled dLLM inference and addresses it with an I/O-aware fused KV-cache kernel that reduces redundant memory movement. Building on this optimized cache mechanism, Flash-dLLM further proposes an efficient KV-cache-driven draft-and-verify decoding strategy, where the dLLM itself serves as both drafter and verifier without requiring an auxiliary model. This unified design enables faster decoding while preserving generation quality and improving scalability to longer sequences and larger batch size. Extensive experiments on mathematical reasoning and code-generation benchmarks demonstrate that Flash-dLLM consistently outperforms existing state-of-the-art dLLM acceleration methods in both inference speed and memory efficiency. In particular, it achieves 5.1and 11.0speedups over prior strongest baseline Elastic-Cache on GSM8K and HumanEval, respectively.
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FleXray: Universal Clinical X-ray Segmentation
X-ray is medicine's most widely used imaging modality, yet remains among its least quantitative. Unlike volumetric modalities like CT or MRI, X-ray collapses 3D anatomy into a 2D projection, causing structures to overlap and anatomical boundaries to be ambiguous, even to experts. As a result, labeling X-ray databases for training general-purpose segmentation systems is impractical, leaving morphometric and functional X-ray analysis confined to narrow anatomical regions and applications. To this end, we present FleXray, a generalist model for anatomical segmentation across the entire body in clinical X-rays. Instead of curating large, manually annotated X-ray datasets, we build a scalable, physics-based generative X-ray data engine. Using existing 3D whole-body CT segmentation datasets and generative image-editing models, we simulate fully-annotated 2D X-rays with diverse appearances, physiological properties, and imaging geometries. Trained on these simulations, FleXray accurately segments 60 anatomical structures across unseen research datasets and in-the-wild X-rays. We further show that FleXray makes X-rays directly amenable to quantitative analysis, enabling automated measurements for disease grading, robust navigation during X-ray-guided interventions, and data-efficient learning of pathological targets. We release the model, code, a full-body X-ray segmentation dataset, and a local, easy-to-use browser-based tool at https://flexray.csail.mit.edu .
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Diffusion-Induced Spatial Attention Overlapping Community Detection
Detection of overlapping communities is essential for modelling networks in which nodes participate simultaneously in multiple structural or functional groups. Existing graph neural network approaches commonly rely on local message passing, which can obscure community boundaries through smoothing and limit the representation of structurally relevant long-range dependencies. We introduce Diffusion-Induced Spatial Attention Community Detection (DISCO), a deep-learning framework that combines a structural prior derived from influence spreading dynamics, sparse multi-head attention, and non-negative community-affiliation learning. The prior identifies candidate interactions beyond immediate graph neighbours and biases attention according to their structural proximity, while a Bernoulli-Poisson edge-reconstruction objective enables overlapping community inference from node attributes and structural profiles, or both. Benchmark experiments show that DISCO performs competitively against established graph convolutional and graph attention approaches across different input configurations. To demonstrate its practical applicability, we present a proof-of-concept cybersecurity use case in which changes between community assignments inferred from consecutive communication-network snapshots provide an interpretable anomaly signal. Temporal community similarity identifies structural deviations, while node-level contributions help locate the devices associated with them. DISCO therefore provides both a flexible method for overlapping community detection and a foundation for analysing structural change in dynamic networks.
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Optimal Sequential Annotations for Off-Policy Evaluation
Offline reinforcement learning and off-policy evaluation evaluates dynamic treatment rules based on retrospectively collected data prior to deployment. In recent AI applications, state and reward information is recorded as complex text or image, which recent AI advancements such as LLM-as-a-judge can label with unknown bias. Expert annotation may be available but at a higher cost. For example, safety classification via cheap but imperfect classifiers vs. expensive expert review. We show how a limited budget for ground-truth data-annotation can be used via doubly-robust OPE with missing rewards, and we optimize variance-optimal annotation probabilities for sequential off-policy evaluation, where the target policy value is estimated from annotated data. We characterize the optimal annotation probabilities for sequential forward-monotone annotation protocols, and provide a feasible batch-adaptive implementation. Our work is motivated by a collaboration with a homelessness services nonprofit that writes casenotes for individuals over time. Our method can be used to unlock trustworthy inference from casenote data and answer new inferential questions such as: how does expanding outreach effort over time affect progress towards a housing application and improvement in housing placement? In simulations and on two real datasets - casenotes from the nonprofit and human-preference votes from LMArena - we see reductions in RMSE of 34-65% for housing placement and 17-68% for progress towards a housing application at budgets of 40% of full annotation and above, and by 55-62% at every budget on LMArena.
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PROSWIN: Probabilistic Solar Wind Speed Forecasting Using Deep Distributional Regression From Solar Images
Accurately predicting fast solar wind conditions is challenging, as uncertainties are large and unquantified by traditional single-value prediction models. In particular, the risks of high-speed solar wind streams (HSSs), which can cause damage to technological infrastructure, cannot be reliably assessed without probabilistic forecasts. We present PROSWIN, a probabilistic machine learning model that forecasts the hourly solar wind speed (SWS) at Earth with a four-day lead time. The approach combines solar images and magnetograms using a deep neural network coupled to a distributional regression algorithm. Because standard error metrics underweight the relevance of HSS peaks, we further introduce the prediction score, a model-selection metric that jointly rewards timeline and HSS peak accuracy. On 14 years of data, our forecast achieves very well-calibrated uncertainties (<1% average deviation). Using the continuous ranked probability score (CRPS), a metric that assesses distributional accuracy, we obtain a timeline CRPS of 41.0 km/s, an HSS peak CRPS of 45.3 km/s, and a prediction score of 42.3 km/s. We find that the 171 Å channel is an important complement to the typically used 193 Å and 211 Å channels and that the prediction score for model selection improves the applicability of the model. Compared to selected models from the literature, ours is the only one that is accurate for both timeline and HSS peak values, rather than trading one off against the other. These results support the advantages of probabilistic over single-value solar wind models. The introduced methods are also transferable to other forecasting problems.
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Diffusion Drafts, AR Verifies: Accelerating Document OCR with Self-Speculative Decoding
Autoregressive OCR vision-language models accurately convert document images into text and structured markup, but require one sequential decoding step per output token, limiting inference speed. Unlike open-ended text generation, OCR outputs are strongly grounded in the input image, making diffusion-based parallel generation promising. However, when several tokens are predicted in one diffusion step, each is predicted before the others are known. Committing them directly can therefore introduce errors. We therefore introduce GravityOCR, a parameter-shared AR-block-diffusion model jointly trained for parallel drafting and causal AR verification. Verifying drafts before commitment lets the model commit multiple output tokens per round without a separate drafting network. The causal AR path also enables GRPO with sequence- and structure-level OCR rewards, avoiding diffusion-trajectory likelihood estimation while updating the shared drafter parameters. On OmniDocBench v1.6, AR-path GRPO improves the Overall score from 94.92 to 95.16 without reducing diffusion drafting efficiency, while the final model remains close to the original GLM-OCR score of 95.48. In an SGLang serving deployment, GravityOCR commits an average of 9.7 output tokens per forward pass and achieves a 3.94decode-only speedup on region crops and a 1.32end-to-end page-processing speedup over AR decoding.
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Label-Efficient Learning for Ground-Based Sky-Image Classification: A Benchmark of Transfer Learning, Active Learning, and Pseudo-Labeling on GCD
Accurate ground-based cloud classification is important for atmospheric monitoring, solar-energy forecasting, aviation weather assessment, and climate observation systems. However, reliable sky-image annotation is time-consuming, especially when cloud types are visually similar or mixed. We study the label efficiency of deep learning for ground-based cloud classification using the Ground-based Cloud Dataset (GCD). Rather than proposing a new architecture, we benchmark three practical strategies under limited annotation budgets: supervised transfer learning, uncertainty-based active learning, and high-confidence pseudo-labeling. An ImageNet-pretrained ResNet50 is used as a common frozen backbone, with experiments repeated over five random seeds for label budgets from 1\% to 100\% of the training labels. Supervised transfer learning is already highly label-efficient: test accuracy increases from 0.635 0.018 with 1\% labels to 0.730 0.002 with 40\% labels, approaching the full-label result of 0.735 0.003. Active learning and pseudo-labeling are competitive with supervised sampling and provide small improvements for some metrics and budgets, but neither gives a large or consistent aggregate gain. Diagnostic analyses show that accepted pseudo-labels are reliable, with accuracy from 0.946 to 0.977, but biased toward easier high-confidence sky-type groups. In contrast, uncertainty sampling preferentially queries visually challenging groups, including Mixed and the confusable Stratocumulus and Cumulonimbus groups, but these targeted acquisitions yield only modest gains. Overall, transfer learning substantially reduces annotation requirements for GCD, while simple active and semi-supervised strategies provide limited additional benefit over a strong supervised baseline.
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MMAP: Multimodal Missing-Aware Pretraining for Longitudinal Alzheimer's Prediction
Clinical decision making heavily relies on predicting the disease progression trajectory by seeking to understand patient's health status which is characterised by multimodal medical data. AI holds great potential for learning useful representations from multimodal medical data to predict disease progression and aid clinical decision making. However, development of predictive AI models is constrained by missing modalities and incomplete tabular data frequently occurring in medical datasets. In addition, disease labels alone may only provide limited supervisory signals for learning representations from high-dimensional multimodal data. Here, we present MMAP, a novel Multimodal Missing-aware Alignment Pretraining method for learning image-tabular representations from incomplete data. An image encoder is pretrained with efficient sigmoid contrastive learning combined with generative reconstruction. A tabular encoder is built upon a tabular foundation model. A missing token generator enables the two encoders to take incomplete data as input, enabling the model to be robust against missing modalities, either with missing images or missing tabular data. We evaluate the clinical usefulness of the learnt multimodal representations on two challenging longitudinal clinical tasks for Alzheimer's disease: predicting disease stage conversion and predicting amyloid status. The proposed method outperforms strong multimodal and unimodal baselines.
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