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Google Cloud launches Gemini for healthcare to unify clinical data and automate workflows. Reduce administrative burnout. See how it works.
Large language models (LLMs) are increasingly used in biomedical and cognitive neuroscience, but their ability to reason reliably over heterogeneous knowledge graphs (KGs) remains unclear. We benchmark five LLMs (GPT-5.1, Gemini 2.0 Pro, Llama 3, Qwen, and BioGPT) across five KGs: DrugBank, NeuroSynth, Cognitive Atlas, Brain Map, and GDPKG. We introduce a multitier query dataset to evaluate reasoning depth and factual accuracy under KG-aware (graph-grounded) and KG-agnostic conditions. Inter-annotator agreement was substantial, with Cohen's kappa of 0.781 (range: 0.753-0.807) and Fleiss' kappa of 0.77. Results show that general-purpose models, particularly GPT-5.1 and Gemini 2.0 Pro, generally outperform domain-specific models on multi-hop and high-level reasoning tasks, although performance declines as query complexity increases. KG grounding reduces hallucination rates across all evaluated models. Contrary to our initial hypothesis, domain-specific models do not consistently outperform general-purpose models on specialized tasks without graph grounding. These findings highlight the value of combining broad language-model capabilities with structured domain knowledge. We provide practical guidance for selecting LLM-KG integration strategies based on task complexity and computational constraints, and discuss hybrid neurosymbolic architectures for personalized medicine, cognitive disorder diagnosis, and explainable AI.
Text "Gemini Introducing Gemini Omni 1.2 Flash" surroudned by images of a beehive, animals in conversation, a squid, and a woman walking down a street
How our engineering team ran Gemini 4 Argon unattended overnight with .agents/skills and /goal mode to cut in-memory session prep overhead by 40% in long sessions and speed up cold imports by 21% in Google's open-source Python Agent Development Kit (ADK).
Today on Decoder, I’m joined by Joey Brookhart, an analyst at the chip and AI research firm SemiAnalysis, to help me dig into the story…
Recent advances in frontier AI models have demonstrated remarkable capabilities in visual understanding, reasoning, planning, and tool use, raising the possibility of using general-purpose AI models for robot manipulation without task-specific training. However, their manipulation capabilities have not been systematically evaluated on standardized robotics benchmarks. In this report, we present a unified closed-loop manipulation framework for evaluating frontier AI models on the LIBERO-10 benchmark. Our framework enables models to control a robot directly through visual observations, robot proprioception, and structured tool calls, primarily by specifying target end-effector poses and gripper commands, without task-specific fine-tuning or pretrained manipulation skills. We evaluate six frontier AI models, including GPT-6 Astra, GPT-6.1 Sol, GPT-6 Luna, Claude Opus 5, Claude Opus 5.5, and Gemini-4 Argon, across three reasoning effort levels, resulting in 18 configurations and 1,800 evaluation episodes. Our results show that GPT-6 Astra achieves the highest success rate of 44%, followed by Gemini-4 Argon at 43%. Increasing reasoning effort generally improves manipulation performance, but the benefits vary across models and come at additional inference cost. We also observe substantial differences across tasks, with models performing relatively well on object placement tasks but struggling with precise spatial arrangements and complex multi-step interactions. These findings demonstrate both the potential and limitations of frontier AI models for robot manipulation, highlighting the challenges of translating reasoning capabilities into reliable physical actions. We release our evaluation framework and experimental results to support reproducible benchmarking and future research on reasoning-based robot manipulation.
